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Patients should be counseled to maintain consistent timing of levothyroxine administration and to report any gastrointestinal side effects from semaglutide that might affect medication-taking behavior

Storage conditions directly affect potency, and degraded semaglutide can deliver less active compound per milligram than the label states

They are not risk-free

The power of pairing GLP-1s with WW Points Program Science shows that weight-loss medications should be combined with lifestyle changes

Results vary, but clinical studies and real-world data show that many individuals lose 5% to 10% of their body weight by the 12-week markespecially if they reach at least the 1 mg or 1.7 mg dose by that point